diff --git a/rpcs3/Emu/System.cpp b/rpcs3/Emu/System.cpp
index c5b663e74b..298151e3bf 100644
--- a/rpcs3/Emu/System.cpp
+++ b/rpcs3/Emu/System.cpp
@@ -279,9 +279,32 @@ void init_fxo_for_exec(utils::serial* ar, bool full = false)
 	}
 }
 
-// Some settings are not allowed in certain PPU decoders
+// Some settings are not allowed with certain conditions
 static void fixup_settings(const psf::registry* _psf)
 {
+	// Disable some incompatible settings in headless mode
+	if (Emu.IsHeadless())
+	{
+		if (g_cfg.video.renderer != video_renderer::null)
+		{
+			sys_log.warning("The video renderer '%s' is currently not supported in headless mode and will therefore be set to '%s'.", g_cfg.video.renderer.get(), video_renderer::null);
+			g_cfg.video.renderer.set(video_renderer::null);
+		}
+
+		if (g_cfg.io.camera == camera_handler::qt)
+		{
+			sys_log.warning("The camera handler '%s' is currently not supported in headless mode and will therefore be set to '%s'.", g_cfg.io.camera.get(), camera_handler::null);
+			g_cfg.io.camera.set(camera_handler::null);
+		}
+
+		if (g_cfg.audio.music == music_handler::qt)
+		{
+			sys_log.warning("The music handler '%s' is currently not supported in headless mode and will therefore be set to '%s'.", g_cfg.audio.music.get(), music_handler::null);
+			g_cfg.audio.music.set(music_handler::null);
+		}
+	}
+
+	// Some settings are not allowed in certain PPU decoders
 	if (g_cfg.core.ppu_decoder != ppu_decoder_type::_static)
 	{
 		if (g_cfg.core.ppu_use_nj_bit)
diff --git a/rpcs3/Emu/System.h b/rpcs3/Emu/System.h
index 99c570b809..a765616c0d 100644
--- a/rpcs3/Emu/System.h
+++ b/rpcs3/Emu/System.h
@@ -172,6 +172,7 @@ class Emulator final
 
 	bool m_continuous_mode = false;
 	bool m_has_gui = true;
+	bool m_headless = false;
 	bool m_add_database_config = false;
 
 	bool m_state_inspection_savestate = false;
@@ -472,6 +473,9 @@ public:
 	bool HasGui() const { return m_has_gui; }
 	void SetHasGui(bool has_gui) { m_has_gui = has_gui; }
 
+	bool IsHeadless() const { return m_headless; }
+	void SetHeadless(bool headless) { m_headless = headless; }
+
 	void SetDefaultRenderer(video_renderer renderer) { m_default_renderer = renderer; }
 	void SetDefaultGraphicsAdapter(std::string adapter) { m_default_graphics_adapter = std::move(adapter); }
 
diff --git a/rpcs3/headless_application.cpp b/rpcs3/headless_application.cpp
index cd8e027f57..fc72801da4 100644
--- a/rpcs3/headless_application.cpp
+++ b/rpcs3/headless_application.cpp
@@ -24,7 +24,7 @@ headless_application::headless_application(int& argc, char** argv) : QCoreApplic
 bool headless_application::Init()
 {
 	// Force init the emulator
-	InitializeEmulator(m_active_user.empty() ? "00000001" : m_active_user, false);
+	InitializeEmulator(m_active_user.empty() ? "00000001" : m_active_user, false, true);
 
 	// Create callbacks from the emulator, which reference the handlers.
 	InitializeCallbacks();
diff --git a/rpcs3/main_application.cpp b/rpcs3/main_application.cpp
index 03426d9a97..0936089f6f 100644
--- a/rpcs3/main_application.cpp
+++ b/rpcs3/main_application.cpp
@@ -61,9 +61,10 @@ namespace rsx::overlays
 extern void qt_events_aware_op(int repeat_duration_ms, std::function<bool()> wrapped_op);
 
 /** Emu.Init() wrapper for user management */
-void main_application::InitializeEmulator(const std::string& user, bool show_gui)
+void main_application::InitializeEmulator(const std::string& user, bool show_gui, bool headless)
 {
 	Emu.SetHasGui(show_gui);
+	Emu.SetHeadless(headless);
 	Emu.SetUsr(user);
 	Emu.Init();
 
diff --git a/rpcs3/main_application.h b/rpcs3/main_application.h
index dd0806970d..f10adda17a 100644
--- a/rpcs3/main_application.h
+++ b/rpcs3/main_application.h
@@ -11,7 +11,7 @@ class main_application
 public:
 	virtual bool Init() = 0;
 
-	static void InitializeEmulator(const std::string& user, bool show_gui);
+	static void InitializeEmulator(const std::string& user, bool show_gui, bool headless);
 
 	void SetActiveUser(const std::string& user)
 	{
diff --git a/rpcs3/rpcs3qt/gui_application.cpp b/rpcs3/rpcs3qt/gui_application.cpp
index 768dcdfc74..026e98cedd 100644
--- a/rpcs3/rpcs3qt/gui_application.cpp
+++ b/rpcs3/rpcs3qt/gui_application.cpp
@@ -152,7 +152,7 @@ bool gui_application::Init()
 	}
 
 	// Force init the emulator
-	InitializeEmulator(m_active_user, m_show_gui);
+	InitializeEmulator(m_active_user, m_show_gui, false);
 
 	// Create callbacks from the emulator, which reference the handlers.
 	InitializeCallbacks();
diff --git a/rpcs3/rpcs3qt/user_manager_dialog.cpp b/rpcs3/rpcs3qt/user_manager_dialog.cpp
index 48e017ea8f..8c96992b2a 100644
--- a/rpcs3/rpcs3qt/user_manager_dialog.cpp
+++ b/rpcs3/rpcs3qt/user_manager_dialog.cpp
@@ -365,7 +365,7 @@ void user_manager_dialog::OnUserLogin()
 	const u32 key = GetUserKey();
 	const std::string new_user = m_user_list[key].GetUserId();
 
-	main_application::InitializeEmulator(new_user, Emu.HasGui());
+	main_application::InitializeEmulator(new_user, Emu.HasGui(), Emu.IsHeadless());
 
 	m_active_user = new_user;
 	m_persistent_settings->SetValue(gui::persistent::active_user, QString::fromStdString(m_active_user));